Hence, such gene induction may correlate with various neurological and immune-related symptoms of ME/CFS, as an estimated 38-55% of ME/CFS patients have symptoms that overlap with other autoimmune diseases (501)
A high-affinity, saturable transport mechanism for DSIP at the blood-brain barrier was demonstrated in vascularly perfused guinea pig brain, with the highest unidirectional transfer rate in the hippocampus (Kin 1.66 L/min/g) [9]
2001;10 Sultana R, Begum R, Haque MM
Evangelista JF, Meirelles CM, Aguiar GS, Alves R, Matsuura C
This ligand is particularly notable for its ability to exploit multiple transport pathways, including LRP-1 and scavenger receptor-mediated routes
Sports 23 (5), 614619