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NLR proteins are an important class of cytoplasmic PRRs that play a key role in microbial sensing, thereby triggering antimicrobial immune responses ( Function of Palmitoylation in Sensing DNA and RNA Since all viruses possess genomes that differ from host nucleic acids and generate additional nucleic acid intermediates during replication, innate immune detection of viruses relies on the nucleic acid sensing system ( Figure 3 )

Atrophic gastritis where the stomach lining becomes thinner

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That can impact body weight over timeagain, indirectly

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Am J Respir Crit Care Med 2011