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doi: 10.1038/s43586-023-00205-2

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In intestinal epithelial cells (IECs) with reduced GPX4 activity, PUFAs and specifically AA induce the release of interleukin 6 (IL-6) and chemokine (C-X-C motif) ligand 1 (CXCL1) which is governed by iron availability, lipoxygenase-mediated LPO and Acsl4

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