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If necessary your GP will prescribe intramuscular injections
How long tirzepatide takes to work is typically 1-2 weeks for appetite effects and 4-8 weeks for measurable weight loss
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While direct cortisol measurements were not specifically reported in the published safety trials, the comprehensive metabolic monitoring across 900+ participants showed no clinically significant hormonal changes, and the mechanism of action provides no pathway for cortisol stimulation
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