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The main cause of CFS is functional vitamin B12 deficiency, however, vitamin B12 levels may be normal or higher than normal and present as Paradoxical B12 deficiency

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Clinical guidance sources recommend baseline serum copper and ceruloplasmin before initiating injectable GHK-Cu, with periodic rechecks during ongoing therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] Song S, Attia RR, Connaughton S, Niesen MI, Ness GC, Elam MB, et al

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