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Heavy drinking depletes hepatic glutathione by 5080% within hours, creating a bottleneck where acetaldehyde accumulates faster than ALDH2 can clear it

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10.1016/j.semcdb.2011.02.021 Semin

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With its two activating groups, the benzene ring is highly reactive towards electrophilic aromatic substitution

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Clinical trial objectives The purpose of the clinical study in humans was to evaluate the efficacy of four weeks supplementation of a combination of vitamin B6, B9, B12, and taurine on motivated behavior, as a primary outcome, and on attentional performance, and self-reported mood (e.g., fatigue, vigor) as secondary outcomes

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