macule melanotic Oral pathology: Noting a pigmented that often presents a diagnostic dilemma Oral melanoacanthoma and oral melanotic

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When glutamate release exceeds glutamate uptake, the excess glutamate activates a large number of postsynaptic NMDA-Rs, resulting in the induction of excitotoxic neuronal death by allowing excessive Ca 2+ influx through the receptor-operated cation channels [73]

Activation of NRF2 reduces iron absorption, limits ROS production, and enhances cellular antioxidant capacity (87)

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Widely studied organelles such as mitochondria, lysosomes, the endoplasmic reticulum and the Golgi apparatus have been confirmed to be involved in the regulation of ferroptosis through a variety of mechanisms, and oxidative damage to the lipid bilayer membrane of organelles is the core mechanism