503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices
Description 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that consumes NAD+ precursors and is reported to be elevated in aged adipose tissue, obese skeletal muscle, and certain tumor types
The treatments were done in a very timely manner
Batch: GF-AOD10-B241 Key analytical results include: Assay Content: 11.48 mg Identification Retention Time: 0.986 Identification Spectrum: 995 Purity: 99.7 percent Bacterial Endotoxins: below 0.001 EU per mg Total Aerobic Microbial Count: not detected Total Yeast and Mold Count: not detected Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium
doi:10.3390/jcm13082176
5-Amino-1MQ functions as a competitive inhibitor at the nicotinamide substrate site of NNMT, with an IC50 of 1.2 M against human NNMT
