Khansaheb M, Choi JY, Joo NS, Yang YM, Krouse M, Wine JJ
Unlike the other two lipid modifications, S-palmitoylation achieves modification through unstable thioester bonds, a property that makes it the only reversible modification of protein lipidation ( Table 1 )
Gall F, Valeriani F, Cattaruzza MS, Gianfranceschi G, Liguori R, Antinozzi M, Mederer B, Liguori G
It is generally used for conditions such as melasma, sun damage, and postinflammatory hyperpigmentation
doi: 10.1007/s10072-009-0090-2 107 SantosP.HerrmannA
The proposed mechanism involves potentiation of existing opioid tone rather than direct opioid receptor agonism, which may explain the absence of classical tolerance and dependence patterns