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Altogether, these pathways form a tightly integrated network, where oxidative stress, inflammatory signaling, and apoptosis reinforce one another, while regulatory pathways such as Nrf2/HO-1, SIRT1, and -Klotho are suppressed, shifting the cellular balance toward damage and follicular loss

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doi: 10.1152/ajpgi.00022.2022 211 FarooqARichmanCMSwainSMShahidRAVignaSRLiddleRA

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The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides

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