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Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events
Reductions in inflammatory markers appeared to correlate with improvements in glycemic control and weight loss, though the independent contribution of tirzepatide remains under investigation
Most evidence comes from the broader growth hormone literature rather than CJC-1295 specific trials
The theoretical concern most often raised relates to BPC-157s angiogenic properties
Meanwhile, overall aging indicators were significantly improved: locomotor activity and endurance were enhanced, hair gloss increased, levels of aging-related inflammatory factors (such as TNF-, IL-6) decreased, and the average lifespan of mice was prolonged