The cause of PCOS is multifactorial, but the combination of genetic predisposition and eipgenetic impacts from environmental factors which switch on or off genes, make a woman with PCOS more prone to insulin resistance and chronic inflammation
Common signs include fatigue, muscle or joint pain, skin rashes, and digestive issues
Metabolic imbalances, especially in lipid and glucose metabolism, are often accompanied by increased ROS, leading to oxidative stress that further damages the vascular endothelium, inhibits NO production, and impairs vascular regulation [262, 263]
This medicine operates by promoting the formation of new blood vessels
Psychiatry 26 , 41914204 (2021)
Topical application (well-studied): Serums at 0.1-0.5%, creams at 0.2-1%, hair products at 0.1-0.3%