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380 Another primary astrocytopathy linked to dysregulated iron homoeostasis is aceruloplasminemia, an autosomal recessive neurodegenerative disease caused by a loss of function mutations of the gene encoding ceruloplasmin, an enzyme that converts ferrous iron to ferric

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In vitro studies using pancreatic acinar AR42J cells exposed to cerulein/resistin-induced oxidative stress and inflammation demonstrated that ALA alleviates these effects by activating the peroxisome proliferator-activated receptor gamma (PPAR) pathway

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