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HGF promotes angiogenesis and neurogenesis, potentially improving nerve regeneration

10.1126/science.abb8925 Science

have previously shown that GSH-dependent glutathione peroxidase 4 (Gpx4) activity is critical for MZB compared to FoB 33

By neutralizing the reactive oxygen species that act as triggers for mast cell degranulation, glutathione helps stabilize these hyperactive immune cells, reducing the systemic flood of histamine and inflammatory cytokines

[DOI] [PubMed] [Google Scholar] 103.Richie J.P., Jr., Muscat J.E., Ellison I., Calcagnotto A., Kleinman W., El-Bayoumy K