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First, more animal models and clinical data are needed to clarify the actual occurrence and mechanistic roles of trained immunity in various inflammatory disorders

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These present a continuous endothelium that is in intimate contact with the cardiomyocytes (only 1 m apart), allowing for direct cellular communication and signaling, and thus regulating their function [20, 34]

Clin Chim Acta 209, 10921

doi: 10.1111/jcmm.18377 53 XuWZhangBXiCQinYLinXWangBet al