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The implication of mitochondria in AS pathophysiology is not entirely surprising since mitochondria serve as the hub of multiple critical cellular processes that affect cell viability and functionality beyond ATP production, such as calcium signaling, apoptosis, and neuronal excitability [14,15,16,17,18,19]
10.1042/BJ20150942 2 Aksoy.KkkeeciH.SevgiF.Metin.Hatay PatirI
Others are chemically fragile
As previously stated in this review, GSH is the most abundant intracellular antioxidant and plays major roles in the antioxidant defense system and maintenance of redox homeostasis in both the PNS and CNS (Hristov BD, 2022)
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