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The presence of polarity and tightness generate a basal PD across epithelial tissue that is measured in the Ussing chamber using voltage electrodes

In a frequently cited study, GHK-Cu introduced by repeated injection into stainless-steel wire-mesh wound chambers implanted subcutaneously in rats produced a concentration-dependent increase in the accumulation of connective tissue, raising dry weight, DNA, total protein, collagen, and glycosaminoglycan content at the repair site, while an inactive control tripeptide did not

Molecular Aspects of Medicine, 30, 4259

91% of users maintain results through week 48

While GHK-Cu occurs naturally in the body and has been used topically for decades, repeated subcutaneous or intramuscular injection of supraphysiological doses is a different proposition