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doi: 10.1074/jbc.271.20.12063 59 LeeW

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470 Mechanically, SCFAs induce fatty acid biosynthesis enzymes, including stearoyl-CoA desaturase 1 (SCD1) and FASN

Numerous studies indicate that, in many tumors, flux through the reductive carboxylation pathway toward lipogenesis can exceed the flux of glutamine oxidation through the citric acid cycle 226,227,228,229

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