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They were shown to non-toxically penetrate cells, ignoring membrane receptors, thereby avoiding limits on efficiency due to receptor saturation (Ross et al., 2018)

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Side effects are rare but can include mild irritation at the injection site

Semaglutide and tirzepatide are GLP-1 receptor agonists that work primarily through appetite suppression and delayed gastric emptying, producing weight loss by reducing caloric intake

The major portion is excreted within the first 24 hours

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