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Third, dose-ranging animal safety studies focused specifically on copper accumulation across repeated systemic dosing would define whether a therapeutic window plausibly exists

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Furthermore, GPER regulates cellular energy metabolism via the AMPK pathway, which may indirectly influence calcium handling [133]

The Connectivity Map is a database that contains more than 7,000 gene expression profiles of 5 human cell lines treated with 1,309 distinct small molecules [ 30 ]

Started with 0.25 mg subcutaneous injections daily, about two inches from the burn site