It is important to be honest about the evidence base: much of the research on BPC-157 and thymosin beta-4 comes from preclinical and animal studies, and large long-term human trials are still limited
Long-Term Consequences of Repeated Excess Dosing Some patients intentionally run BPC-157 at doses above published protocols, reasoning that more peptide will accelerate healing
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Given as individual agents to healthy rats, all dopamine antagonists (central [haloperidol (6.25 mg, 16 mg, 25 mg), fluphenazine (5 mg), levomepromazine (50 mg), chlorpromazine (10 mg), quetiapine (10 mg), olanzapine (5 mg), clozapine (100 mg), sulpiride (160 mg), metoclopramide (25 mg)) and peripheral(domperidone (10 mg)], l-NAME (5 mg) and l-arginine (100 mg) decreased the pressure within both sphincters
PARP (another cell death marker) was reduced by 77.5%