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This regulatory status reflects the absence of completed human clinical trials establishing safety and efficacy to approval standards

[DOI] [PubMed] [Google Scholar] 64.Feng B., Yan X.F., Xue J.L., Xu L., Wang H

21 December 2018

Advanced drug delivery systems provide opportunities to mitigate caudatins toxicity and bioavailability shortcomings by improving solubility with nanocarrier platforms (liposomes or polymer nanoparticles utilizing the EPR effect for tumor-specific delivery), decreasing overall exposure to the liver and kidneys

These findings establish the AEDG sequence as one of the most well-documented peptide tools in telomere biology research

10.1021/jp908251z 20 DouradoD