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In contrast, the BDNF kits from Aviscera Bioscience (#SK00752-01) and FineTest (#EH0043), marketed for quantifying mature BDNF, were more specific for pro-BDNF, as mentioned above (Figs
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Wrbel H (2020) The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Collectively, these factors result in exceedingly low bioavailability, defined as the fraction of the ingested compound that reaches systemic circulation in an active form, thereby limiting the therapeutic and nutritional efficacy of such agents
Ma D, Sun D, Wang C, Ding H, Qin H, Hou J et al (2017) Physiological responses and yield of wheat plants in zinc-mediated alleviation of drought stress