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The primary outcomes were the percentage weight change and the proportion of participants losing at least 5% of their baseline weight, using treatment-policy estimand analysis (intention-to-treat principle)

Transwell inserts allow the endothelial cells to grow on a membrane that sits in a stagnant tissue culture plate and is useful to measure the barrier properties of the subsequent monolayer

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PTMs are critical molecular events in a series of biological processes such as cell growth, proliferation, differentiation, metabolism, and apoptosis ( Protein oxidation Cysteine residues in proteins are easily oxidized by ROS, reactive nitrogen species, reactive sulfur species, or GSH

Oral L-carnitine is readily absorbed across the intestinal mucosa and into the bloodstream

Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation