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Although risen from a single common ancestor, their substrate specificity and diversity have been reshaped by gene duplication, genetic recombination, and an accumulation of mutations

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In turn, TREM2 has been described to sense a wide range of lipids associated with fibrillary A and exposed during neuronal degeneration [62]

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Much of the published literature involves in vitro and animal models investigating mucosal protection, angiogenesis, and musculoskeletal repair biology

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