While several therapies, i.e., drug therapy, surgical resection, immunotherapy and radiotherapy, have demonstrated their efficacy in treating CRC, they may have specific drawbacks [7-10]
10.3389/fvets.2025.1621738 Front Vet Sci
writingoriginal draft preparation, D.B., M.-H.G.P., D.M., M.-C.B
Here's the real challenge, and we can't stress this enough: spinal discs have a terrible blood supply
Our preliminary interpretation is that replacement of Tyr110 indeed affects the interaction with GSH but, as compared to K105A/Y, does not drastically alter the ratio between the steady-state concentrations of the deprotonated and glutathionylated enzyme species E and F, respectively
doi: 10.1007/s11306-022-01886-8 6 BanachM.GurdzielE.JdrychM.BorowiczK