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Similar challenges exist with complementary therapies, where acupuncture and certain Chinese herbal formulations show potential benefits in IBS, but variability in composition and lack of standardization hinder adoption [123, 124]

NG239 Diagnostic tests evidence review (methylmalonic acid and homocysteine)

[2] As of 2019, tesofensine has been discontinued for the treatment of Alzheimer's and Parkinson's disease but is in phase III clinical trial for obesity

However, causal inferences from MR studies require validation through longitudinal cohort studies

Budget constraints matter

Glutathione is a naturally occurring antioxidant made in the body from amino acids such as cysteine, glycine, and glutamic acid