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Some patients may experience an increased likelihood of respiratory infections, including bronchitis or pneumonia

These cases show that both placebo and real biologic responses are part of the picture

For instance, Liu et al

Considering the importance of GH and IGF-1 for brain functions and development, this apparent paradoxical protection may be explained by increased insulin sensitivity (40) and the prevention of age-related activation of the inflammasome and neuroinflammation (41, 42) observed in these mouse models (Figure 2)

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