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Hydroquinone can be medically useful when prescribed and monitored properly for hyperpigmentation

It is not approved for human or animal use , and any therapeutic claims are strictly for preclinical investigation

Herbs such as turmeric, ginseng, ashwagandha, and amla lose potency when exposed to moisture, reducing their antioxidant and adaptogenic effects

216 In addition, PRMT4-catalyzed asymmetric dimethylarginine (ADMA) has been reported to bind to NOS as a ligand, leading to NOS dysfunction, resulting in decreased cerebral blood flow and aggravating AD, which can be reversed by inhibition of PRMT4