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It is postulated that DM-induced oxidative damage may be more significant in erythrocytes than in other cells, due to their high content of iron and polyunsaturated fatty acids, as well as their role as oxygen transporters, with a high degree of exposure to free radicals [320]

Acta Naturae 5 , 4053 (2013)

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35 As discussed earlier, trauma, coupled with an associated genotype, can damage keratinocytes, leading to the expression of IFN and TNF, activation of dendritic cells, and production of IL-23