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Available human information involved melatonin-metabolite or clock-gene measurements without corresponding clinical sleep outcomes

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Although not the focus of this study, an obvious question relates to the identity of the molecular target responsible for the procognitive and synaptogenic activity of dihexa and other AngIV-related compounds

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Cagrilintide is a newer long-acting amylin analogue - in a phase 2 trial, once weekly cagrilintide resulted in a dose-dependent WL between 6 and 10.8% compared to 9% with liraglutide 3 mg and 3% with placebo [87]