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For long-term storage beyond one year, or for vials from a multi-month supply that will not be opened for extended periods, the freezer at -20 degrees Celsius is the better choice, extending stability to two years or more

At the same time, combined with metabolomics, 16S rRNA sequencing and MetOrigin, the compatibility mechanism of XJZ in the treatment of CAG was explored from the changes in intestinal microbiota and metabolites

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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 35% by weight of the poloxamer

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