The fundamental basis of GI motility lies in the intrinsic ability of GISM to generate cyclic changes in resting membrane potential, which give rise to spontaneous and rhythmic contractions (Grundy et al., 1985)
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This means more people can stay on tirzepatide at effective doses compared to semaglutide, which is a meaningful advantage when the goal is long-term use
While first explored as a treatment for shielding the stomach lining, it has subsequently earned awareness due to its restoration abilities in diverse tissues such as tendons