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Therefore factors such as stress, infections, sleep issues & leaky gut may play a role

[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

Smith MA, Sayre LM, Anderson VE, Harris PLR, Beal MF, Kowall N, et al

Some research suggests it helps protect the cells within the enteric nervous system , supporting the nerves that control digestion

[5] Hall et al, Neuroimage 86 : 35-42, 2014

What we found is, as long as people are losing two pounds or less a week, they're not losing the muscle mass