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Blood 1998;92:1191-1198

Most patients begin with a weekly loading phase for 48 weeks, followed by monthly maintenance, with no downtime

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References 1 AkyuzE.DoganyigitZ.ErogluE.MoscoviczF.MerelliA.LazarowskiA.et al (2021)

For individuals with low plasma levels, topical application of vitamin C can be beneficial, particularly when optimized for absorption, such as in acidic conditions or when encapsulated in lipospheric forms

Furthermore, patients with advanced PD are at risk of developing dementia as a result of the accumulation of -Syn in Lewy bodies