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Here are some groups of people who might benefit from B12 supplementation: Vegetarians and Vegans: Since B12 is primarily found in animal products, those who avoid meat, dairy, and eggs may be at risk of deficiency
Kidney failure and liver damage: Untill now, studies in patients with liver damage or renal failure did not detect pharmacokinetic differences, in normal individuals
In support of the idea that cross-protective immunity exists, recent HCoV infections were found to be associated with less severe COVID-19 upon infection with ancestral SARS-CoV-2 [103], and infection with SARS-CoV-2 of any variant was also associated with a reduced incidence of subsequent HCoV infection