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Correcting B12 changes your metabolism and nervous-system signalling, and that adjustment itself can feel like tiredness, lightheadedness or a vague off feeling before things settle

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Plasma riboflavin and vitamin B-6, but not homocysteine, folate, or vitamin B-12, are inversely associated with breast cancer risk in the European Prospective Investigation into Cancer and Nutrition-Varese cohort

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(PubMed) Kwok T, Wu Y, Lee J, et al

Drug Discovery Today , 20 (1), 122128