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156 Another peptidomimetic analogue, TLK117, has been extensively investigated in the context of lung fibrosis

The results demonstrated a very strong accumulation of ROS inside the hypoxic cancer cells upon treatment with NP4 but a poor ROS accumulation upon preincubation with NAC and subsequent treatment with NP4 (flow cytometry plots: Fig

In addition, cells outside the bulge area began to proliferate

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All data were subjected to analysis of variance (ANOVA), and Fishers least significant difference (LSD) test was used to determine significant differences among treatments