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Although cytosolic CPS2 can produce a cytosolic pool of carbamoyl phosphate, CPS1 is a major rate-limiting enzyme in pyrimidine biosynthesis using nitrogen released via mitochondrial glutaminolysis 32

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(PubMed) Kancherla V, Botto LD, Rowe LA, et al

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doi: 10.1089/thy.2015.0176 13 ChenJLiXLZhaoCKWangDWangQLiMXet al

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