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2.2 Hepatic Impairment Study 2.2.1 Study Population Male and female participants of non-childbearing potential aged between 18 and 80 years with a BMI between 18.5 and 39.9 kg/m 2 were eligible for inclusion in the hepatic impairment study

Kidney Function Clinical trials found that kidney disorders occurred at similar rates for semaglutide versus comparators, indicating no increased nephrotoxicity

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Heterogeneity intrinsic to each PAIS represents a major obstacle to the design and implementation of clinical trials

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3 , e1700344 (2017)