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To accomplish this, the trial was designed to focus on the assessment of objective endpoints such as small nerve fiber quantification by using both skin biopsy and corneal confocal microscopy and to relate these findings to semiobjective sensory testing by using QST, which directly assesses the effects of potential changes in cutaneous innervation

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The methyl group is successfully transferred, yielding the essential amino acid methionine and leaving behind a highly reactive intermediate known as cob(I)alamin

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Overall Health General health status and the presence of other medical conditions can impact the speed of results

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