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This small but powerful molecule is produced naturally by our bodies and is found in every cell, playing a crucial role in protecting our cells from oxidative stress and maintaining optimal immune function

The mechanism is likely related to reduced caloric intake and metabolic adjustment rather than a direct drug effect

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Mechanistically, ripasudil safeguarded membrane localization of CD59a, a MAC inhibitor highly expressed on hepatocytes, hindering the MAC formation (Ma et al., 2023)