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Refrigeration isn't just "better" - it can extend usable life by 3-10x depending on the form
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Neurochem Int 51:361369 Liu G-H, Qu J, Suzuki K, Nivet E, Li M, Montserrat N, Yi F, Xu X, Ruiz S, Zhang W et al (2012) Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
If that sounds risky, thats because it is