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Johannsson declares that he has received speaking honoraria and grant support from the following companies: Novo Nordisk, Pfizer

Biochemistry 37, 1270712714

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Some studies have evaluated L-arginine in doses between 2.8 and 6 mg/day for up to 6 weeks, and have reported beneficial effects, - but these studies have not evaluated the subjective improvements using a validated questionnaire, and thus the results remain circumspect

In different cell types, such as endothelial phagocytes, smooth muscle cells, fibroblasts, and glial cells, TNF- and ILs upregulate PTX3 transcription and are involved in atherogenesis