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Sulfonamide antibiotics are one of the most commonly prescribed groups of antibiotics globally in both human and veterinary medicine

X.McQueenT.HsuT.et al (2005)

GCL is specific for the glutamyl moiety and is regulated physiologically by: (a) non-allosteric feedback competitive inhibition by GSH (Ki=2.3mM), which involves binding of GSH to the glutamate and another site on the enzyme [8, 9] and (b) availability of its precursor, cysteine [1] .The apparent Km values of GCL for glutamate is 1.8 mM, and for cysteine and 0.10.3 mM [9]

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It means products stored in temperature-controlled Canadian facilities rather than sitting in shipping containers during cross-border transit

This is Solubility and Molecular Structure, section 13.2 from the book Principles of General Chemistry (v