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In summary, elevated levels of inflammatory factors partly initiated by microglia and other recruited immune cells causes a phenotypic switch in astrocytes that contributes to functionally perpetuating inflammation via the release of pro-inflammatory cytokines and recruitment of peripheral immune cells

In contrast to loss of FOXO4, FOXO4-DRI does not sensitize healthy cells to acute DNA damage (Fig

The parallel to BPC-157 is instructive: theoretical concerns deserve monitoring but should not override evidence of safety

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

Iron deficiency is perhaps the most significant