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Absolute bioavailability compares the bioavailability of active drug in systemic circulation following non-intravenous administration, with the bioavailability of the same drug following intravenous administration

Experientia 52 , 513 (1996)

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Growth factors are universally large proteins that are both metabolically labile and too large to pass the blood- brain barrier (BBB)

Note: If you have a particularly sensitive stomach, taking supplements on a completely empty stomach might cause mild discomfort