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For example, macrophage-derived Exos induce endothelial ferroptosis and barrier disruption during cerebral ischemiareperfusion injury via thrombospondin-1-mediated binding to OTUD5 and promotion of GPX4 ubiquitination [221]

Int J Mol Sci 23(24):15893

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Interestingly, terazosin (TZ) has been shown to enhance PGK1 activity, thereby stimulating glycolysis and increasing cellular ATP levels