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Chk1 phosphorylates p53, thereby modulating its activity [62]

however, production of glutathione may not always be enough to optimize its potential

It regulates the immune system, controls cytokine signalling, and helps keep the inflammatory response in balance

Phospholipase iPLA(2) averts ferroptosis by eliminating a redox lipid death signal

Peptide hormones interact with receptor sites located on the cell surface and initiate a signal transduction cascade which is ultimately responsible for altering gene expression and cell behavior

In any case, only a small percentage of caffeine users ingest such large levels, and those who are sensitive to caffeine's effects in general or who experience its anxiogenic effects are likely to abstain from using it (Bertasi et al., 2021