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Abstract Oxidative stress, disrupted copper homeostasis, and neuroinflammation due to overproduction of proinflammatory cytokines are considered leading causative factors in development of age-associated neurodegenerative conditions

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[5] Notably, normal feedback mechanisms remain intact: elevated IGF-1 and GH can signal the hypothalamus and pituitary to modulate further hormone release, which may reduce the risk of extreme hormone levels

American Journal of Tropical Medicine and Hygiene, 106 (4), 1204-1215

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About EVU Center also offers telemedicine for more convenient patient follow-up